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Liverpool are building up to one of the defining fixtures of their campaign, but instead of calm anticipation, unease surrounds Arne Slot and his squad. As Thursday night approaches, the Reds head to North London to take on an in-form Arsenal side that currently sits comfortably at the summit of the Premier League. The stakes could hardly be higher, with implications stretching across the title race, Champions League qualification hopes, and the psychological momentum heading into the season’s second half.

Yet Liverpool’s focus has been pulled away from tactical plans and matchday strategy. Persistent fitness concerns have dominated preparations, forcing Slot to juggle optimism with realism at a critical moment.

Up to Five Players Could Miss the Emirates Clash

At present, Liverpool risk travelling to the Emirates Stadium without as many as five senior players. Some absences are already confirmed, while others depend on late medical assessments. For Slot, still in the early stages of shaping his Liverpool identity, the timing could not be worse. Arsenal are brimming with confidence, playing sharp, aggressive football, while Liverpool must carefully manage fatigue, recovery, and squad depth all at once.

Ekitike Injury Raises Major Alarm

The most worrying situation revolves around Hugo Ekitike. The French forward has been one of Liverpool’s most reliable performers this season, topping the club’s scoring chart with 11 goals in all competitions. His speed, movement, and ability to stretch defences have given Liverpool a cutting edge, particularly during periods when attacking options have been limited.

However, Ekitike was missing from the squad during the 2–2 draw away at Fulham. Although Liverpool showed flashes of attacking brilliance in that game, his absence was noticeable. Initially, the issue was thought to be minor, but concerns grew when he was not even included among the substitutes.

Hamstring problems are notoriously unpredictable, and with fixtures coming thick and fast, even a slight issue can quickly escalate if mismanaged. Slot acknowledged the concern but maintained a cautious optimism when addressing the situation publicly.

Why Liverpool Chose Not to Take Risks

According to Slot, the early diagnosis suggested Ekitike was dealing with delayed onset muscle soreness (DOMS), a condition common during congested schedules. The hope was that he might still be available off the bench against Fulham if needed. Further medical checks, however, pointed to something more delicate, prompting the club to act conservatively.

The Liverpool boss made it clear that protecting the player’s long-term fitness was the priority. While that approach may pay off later in the season, it has done little to calm nerves ahead of the Arsenal showdown, especially given the situation elsewhere in the squad.

Isak’s Long-Term Absence Compounds the Problem

Liverpool are already without Alexander Isak, who had been expected to play a significant role this season. The Swedish striker faces several months on the sidelines following ankle surgery. His injury occurred in dramatic fashion before Christmas during a narrow away win, when a heavy challenge resulted in a fractured fibula.

Isak’s absence has forced Slot to rethink his attacking setup and lean heavily on players like Ekitike. Without him, Liverpool lack a physically strong forward capable of linking play and occupying defenders. That makes Ekitike’s fitness situation even more crucial. If the Frenchman is unavailable against Arsenal, Liverpool could find themselves short of firepower against one of the league’s most organised defences.

Wirtz Boost Offers Some Hope

There is more encouraging news regarding Florian Wirtz. The German midfielder has been managing his own hamstring discomfort but still featured against Fulham, where he once again underlined his importance by finding the net. His intelligence, creativity, and eye for space have quickly made him central to Liverpool’s attacking rhythm.

That said, caution remains necessary. Hamstring issues rarely disappear overnight, and any lingering discomfort could limit his effectiveness. Slot and his medical team will need to decide whether Wirtz can start at full throttle or whether his minutes need careful management. Against Arsenal’s intensity, there is little margin for compromise.

Salah and Defensive Absences Add to the Challenge

Mohamed Salah is another confirmed absentee, as the Egyptian continues his international commitments at the Africa Cup of Nations. While Liverpool supporters will take pride in his progress with Egypt, his absence is always deeply felt. Salah’s goals, experience, and ability to deliver in big moments are qualities that are almost impossible to replace.

Defensively, Liverpool are also stretched. Young centre-back Giovanni Leoni remains sidelined for the season after ACL surgery earlier in the campaign. Although not a guaranteed starter, his absence reduces depth and flexibility during a period where rotation would be invaluable.

Arsenal Sensing an Opportunity

The combined impact of injuries and international duty leaves Liverpool facing the league leaders with a weakened squad. Arsenal, by contrast, look settled, confident, and ruthless. From their perspective, this fixture represents a chance to reinforce their dominance at the top of the table.

For Liverpool, the task is about more than tactics. They must show resilience, adaptability, and belief, regardless of who is available. Slot has remained composed throughout, choosing not to fuel panic and instead focusing on maximising the resources at hand.

A Defining Moment for Slot’s Liverpool

Matches like this often shape a season’s narrative. A positive result in North London could provide a massive confidence boost and reinforce the belief that Liverpool remain genuine contenders. A heavy defeat, however, would raise uncomfortable questions about squad depth and the ability to withstand adversity.

Much hinges on the final decision regarding Ekitike. Even a limited role could lift morale and force Arsenal to adjust defensively. Without him, Liverpool will need goals from unexpected sources and near-perfect collective discipline.

Final Thoughts

As kick-off draws closer, uncertainty remains. Fitness updates will be scrutinised, training sessions carefully monitored, and difficult decisions made. Some players may push themselves to be involved, while others may be protected for the long haul.

One thing is clear: Liverpool’s trip to the Emirates will test character as much as quality. Injuries are unavoidable in elite football, but how a team responds often defines its identity. Whether patched together or near full strength, Liverpool must show courage, unity, and belief if they are to leave North London with anything to show for their efforts.

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